Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8776124 | 0.98 | — | — | |
| SCHEMBL841367 | 0.81 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL5764422 | 0.78 | — | — | |
| SCHEMBL11373090 | 0.77 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL23978870 | 0.76 | — | — | |
| SCHEMBL780900 | 0.73 | CETP (0.34) | ALDH1A1 | |
| SCHEMBL14533547 | 0.73 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL878835 | 0.73 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL11299703 | 0.73 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL6201919 | 0.72 | ALDH1A1 (0.36) | ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101484413-B | Process for preparing gabapentin | ZACH SYSTEM SPA | 2014-05-14 | — | — | CN | disclosed |
| EP-2038249-B1 | PROCESS FOR PREPARING GABAPENTIN | ZACH SYSTEM SPA (IT) | 2013-09-11 | — | — | EP | disclosed |
| US-8143443-B2 | Process for preparing gabapentin | ZACH SYSTEM S.P.A. (IT) | 2012-03-27 | — | — | US | disclosed |
| US-20100029983-A1 | PROCESS FOR PREPARING GABAPENTIN | ZACH SYSTEM S.P.A. (IT) | 2010-02-04 | — | — | US | disclosed |
| EP-2038249-A1 | PROCESS FOR PREPARING GABAPENTIN | ZaCh System S.p.A. (IT) | 2009-03-25 | — | — | EP | disclosed |
| WO-2008004115-A1 | PROCESS FOR PREPARING GABAPENTIN | ZACH SYSTEM S.P.A. (IT) | 2008-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029983-A1 | PROCESS FOR PREPARING GABAPENTIN | GABRB1, GABRG1, OGDH | ALDH1A1 55/4885GAA 1296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.