Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | CNR2 | P34972 | 2/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 3/20 | 0.48 |
| ▸ | SNCA | P37840 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12472565 | 0.88 | HDAC6 (0.73) | HDAC6HDAC1HDAC8CNR2HDAC10 | |
| SCHEMBL7809792 | 0.87 | HDAC6 (0.62) | HDAC6HDAC1HDAC8CNR2CNR1 | |
| SCHEMBL7815554 | 0.79 | HDAC1 (0.49) | HDAC6HDAC1HDAC8KDM4ECNR2 | |
| SCHEMBL3855963 | 0.78 | CNR1 (0.53) | HDAC6KDM4ECNR2CNR1HDAC10 | |
| SCHEMBL17372069 | 0.77 | HTR2C (0.62) | CNR2CNR1HTR2CAPPSNCA | |
| SCHEMBL11059396 | 0.77 | ALDH1A1 (0.61) | ALDH1A1 | |
| SCHEMBL30632097 | 0.77 | ALDH1A1 (0.61) | ALDH1A1 | |
| SCHEMBL2879361 | 0.77 | GPR84 (0.56) | HDAC6HDAC1HDAC8KDM4EHDAC10 | |
| SCHEMBL3855960 | 0.76 | HTR2C (0.53) | HDAC6HDAC1HDAC8KDM4ECNR2 | |
| SCHEMBL3855969 | 0.76 | HTR2C (0.53) | HDAC6HDAC1HDAC8KDM4ECNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949259-B1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-6184238-B1 | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-02-06 | — | — | US | disclosed |
| EP-0949259-A1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-10-13 | — | — | EP | disclosed |