Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 9/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | GSTP1 | P09211 | 3/20 | 0.50 |
| ▸ | NPY1R | P25929 | 1/20 | 0.50 |
| ▸ | NPY2R | P49146 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7808550 | 0.86 | HTR1A (0.60) | RAB9ASMN1; SMN2NPC1MAPTTSHR | |
| Hydrochloric Acid SCHEMBL1387849 | 0.84 | SLC6A9 (0.58) | RAB9ASMN1; SMN2NPC1MAPTTSHR | |
| Hydrochloric Acid SCHEMBL1387847 | 0.84 | SLC6A9 (0.58) | RAB9ASMN1; SMN2NPC1MAPTTSHR | |
| Hydrochloric Acid SCHEMBL7810704 | 0.81 | SLC6A9 (0.71) | RAB9ASMN1; SMN2NPC1MAPTTSHR | |
| SCHEMBL7816012 | 0.79 | SLC6A9 (0.60) | RAB9ASMN1; SMN2NPC1MAPTTSHR | |
| Hydrochloric Acid SCHEMBL1387856 | 0.78 | SLC6A9 (0.59) | RAB9ASMN1; SMN2NPC1MAPTTSHR | |
| Hydrochloric Acid SCHEMBL1387858 | 0.78 | SLC6A9 (0.59) | RAB9ASMN1; SMN2NPC1MAPTTSHR | |
| SCHEMBL8191218 | 0.77 | SLC6A9 (0.56) | RAB9ASMN1; SMN2NPC1MAPTTSHR | |
| SCHEMBL7812360 | 0.77 | HTR1A (0.64) | RAB9ASMN1; SMN2NPC1MAPTTSHR | |
| SCHEMBL1387863 | 0.74 | RAB9A (0.53) | RAB9ASMN1; SMN2NPC1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767782-B1 | ARYL AND HETEROARYL ALKOXYNAPHTHALENE DERIVATIVES | PFIZER (US) | 2001-10-31 | — | — | EP | disclosed |
| US-6166020-A | Aryl and heteroaryl alkoxynaphthalene derivatives | PFIZER INC. (US) | 2000-12-26 | — | — | US | disclosed |
| EP-0767782-A1 | ARYL AND HETEROARYL ALKOXYNAPHTHALENE DERIVATIVES | PFIZER INC. (US) | 1997-04-16 | — | — | EP | disclosed |
| WO-1996000720-A1 | ARYL AND HETEROARYL ALKOXYNAPHTHALENE DERIVATIVES | PFIZER INC. (US) | 1996-01-11 | — | — | WO | disclosed |