Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7139240 | 0.82 | F2 (0.44) | F2PRSS1 | |
| SCHEMBL7220542 | 0.81 | F2 (0.47) | F2PRSS1 | |
| SCHEMBL7411110 | 0.76 | F2 (0.47) | F2PRSS1 | |
| SCHEMBL7452530 | 0.75 | LMNA (0.42) | F2PRSS1 | |
| SCHEMBL7819200 | 0.75 | F2 (0.46) | F2PRSS1 | |
| SCHEMBL7819546 | 0.75 | F2 (0.41) | F2 | |
| SCHEMBL8188271 | 0.75 | F2 (0.50) | F2PRSS1 | |
| SCHEMBL7404995 | 0.74 | F2 (0.53) | F2PRSS1 | |
| SCHEMBL7451716 | 0.74 | LMNA (0.41) | F2PRSS1 | |
| SCHEMBL3238624 | 0.74 | F2 (0.70) | F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900207-B1 | PYRAZINONE THROMBIN INHIBITORS | MERCK & CO INC (US) | 2001-11-21 | — | — | EP | disclosed |
| US-5866573-A | Pyrazinone thrombin inhibitors | MERCK & CO., INC. (US) | 1999-02-02 | — | — | US | disclosed |