Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 20/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7220542 | 0.79 | F2 (0.47) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7444854 | 0.78 | TPSAB1 (0.43) | F2PRSS1 | |
| SCHEMBL7411110 | 0.78 | F2 (0.47) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7819546 | 0.77 | F2 (0.41) | F2 | |
| SCHEMBL3238624 | 0.76 | F2 (0.70) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7026286 | 0.76 | F2 (0.45) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL5885528 | 0.75 | F2 (0.60) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7459174 | 0.75 | LMNA (0.48) | F2PRSS1 | |
| SCHEMBL7809549 | 0.75 | F2 (0.45) | F2PRSS1 | |
| Hydrochloric Acid SCHEMBL7018692 | 0.75 | F2 (0.45) | F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6011038-A | Pyrazinone thrombin inhibitors | MERCK & CO., INC. (US) | 2000-01-04 | — | — | US | disclosed |