SCHEMBL7809644

SCHEMBL7809644

CCC(O)(c1ccccc1)c1ccccc1C(O)(CC)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.47
HTR2A P28223 1/20 0.46
HTR2C P28335 1/20 0.46
ADRA1A P35348 1/20 0.46
OPRK1 P41145 1/20 0.46
KCNH2 Q12809 1/20 0.46
SIGMAR1 Q99720 1/20 0.46
CHRM4 P08173 4/20 0.43
CHRM5 P08912 4/20 0.43
CHRM3 P20309 4/20 0.43
CHRM2 P08172 3/20 0.43
CHRM1 P11229 3/20 0.43
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
CYP2C9 P11712 3/20 0.40
CYP2C19 P33261 3/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2D6 P10635 1/20 0.40
KCNN4 O15554 1/20 0.40
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11620674 0.90 HTR2A (0.44) SMN1; SMN2HTR2AHTR2CADRA1AOPRK1
SCHEMBL246639 0.88 SMN1; SMN2 (0.52) SMN1; SMN2KCNH2SIGMAR1CHRM4CHRM5
SCHEMBL7923161 0.88 SMN1; SMN2 (0.42) SMN1; SMN2HTR2AHTR2CADRA1AOPRK1
SCHEMBL10816937 0.88 ALDH1A1 (0.47) SMN1; SMN2HTR2AHTR2CADRA1AOPRK1
SCHEMBL11764324 0.86 HTR2A (0.64) SMN1; SMN2HTR2AHTR2CADRA1AOPRK1
SCHEMBL27641846 0.86 SMN1; SMN2 (0.41) SMN1; SMN2HTR2AHTR2CADRA1AOPRK1
SCHEMBL11621137 0.86 KCNN4 (0.46) SMN1; SMN2HTR2AHTR2CADRA1AOPRK1
SCHEMBL11623430 0.86 HTR2A (0.44) SMN1; SMN2HTR2AHTR2CADRA1AOPRK1
SCHEMBL936317 0.86 SMN1; SMN2 (0.50) SMN1; SMN2SIGMAR1CHRM4CHRM5CHRM3
SCHEMBL28539349 0.86 CHRM2 (0.50) SMN1; SMN2KCNH2SIGMAR1CHRM4CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6316170-B2 COATING, EXPOSURE, DEVELOPMENT AND HEAT TREATMENT KABUSHIKI KAISHA TOSHIBA (JP) 2001-11-13 US disclosed
US-20010006767-A1 Developing solution and method of forming polyimide pattern by using the developing solution YOSHIAKI KAWAMONZEN 2001-07-05 US disclosed
EP-0485472-A1 BIS-CYCLIC PHOSPHITE COMPOUNDS AND POLYMERIC MATERIALS STABILIZED THEREWITH EASTMAN KODAK COMPANY (US) 1992-05-20 EP disclosed
EP-0437493-A1 CYCLIC PHOSPHITES AND STABILIZED POLYMERIC COMPOSITIONS EASTMAN KODAK COMPANY (US) 1991-07-24 EP disclosed
WO-1991001987-A1 BIS-CYCLIC PHOSPHITE COMPOUNDS AND POLYMERIC MATERIALS STABILIZED THEREWITH EASTMAN KODAK COMPANY (US) 1991-02-21 WO disclosed
EP-0412028-A1 Bis-cyclic phosphite compounds and polymeric materials stabilized therewith EASTMAN KODAK COMPANY (US) 1991-02-06 EP disclosed
US-4956406-A Oxidation resistance of polypropylene or copolymers also heat resistance and radiation resistance EASTMAN KODAK COMPANY (US) 1990-09-11 US disclosed
US-4929654-A HEAT RESISTANCE, LIGHT RESISTANCE EASTMAN KODAK COMPANY (US) 1990-05-29 US disclosed
WO-1990003976-A1 CYCLIC PHOSPHITES AND STABILIZED POLYMERIC COMPOSITIONS EASTMAN KODAK COMPANY (US) 1990-04-19 WO disclosed
EP-0363270-A1 Cyclic phosphites and stabilized polymeric compositions EASTMAN KODAK COMPANY (US) 1990-04-11 EP disclosed