SCHEMBL7809669

SCHEMBL7809669

CCc1cccc2c(OSC)c(C(C)=O)c(=O)[nH]c12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 3/20 0.40
ALDH1A1 P00352 4/20 0.39
LMNA P02545 3/20 0.39
KDM4E B2RXH2 3/20 0.37
PGR P06401 1/20 0.36
HTT P42858 1/20 0.36
TSHR P16473 3/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
ALOX15 P16050 1/20 0.35
NFKB1 P19838 1/20 0.35
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35
BLM P54132 1/20 0.35
PMP22 Q01453 1/20 0.35
SLC22A6 Q4U2R8 1/20 0.35
DDO Q99489 1/20 0.35
RXFP1 Q9HBX9 1/20 0.34
PIM1 P11309 1/20 0.34
PIM3 Q86V86 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7809500 0.85 KDM4E (0.45) DAOALDH1A1LMNAKDM4ETSHR
SCHEMBL7804026 0.84 RXFP1 (0.45) DAOLMNAKDM4ERXFP1CDK1
SCHEMBL7813789 0.84 FEN1 (0.39) DAOALDH1A1LMNAKDM4EPGR
SCHEMBL7817120 0.81 CAPN1 (0.44) ALDH1A1LMNAKDM4EHTTPIM1
SCHEMBL7809535 0.81 FEN1 (0.42) ALDH1A1LMNAKDM4ETSHRMEN1
SCHEMBL7809663 0.80 DAO (0.38) DAOALDH1A1LMNAKDM4EPGR
SCHEMBL497316 0.78 KDM4E (0.58) DAOALDH1A1LMNAKDM4EBLM
SCHEMBL7809443 0.76 RXFP1 (0.47) DAOKDM4ERXFP1CDK1CCNB1
SCHEMBL7811064 0.72 KDM4E (0.39) ALDH1A1KDM4EHSD17B10GRIN2DGRIN3B
SCHEMBL7812988 0.71 MEN1 (0.34) ALDH1A1PGRALOX15MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0533882-B1 2-QUINOLINONE DERIVATIVES, METHODS FOR PREPARING THE SAME AND FUNGICIDES AND INSECTICIDES INCLUDING THEM KOREA RES INST CHEM TECH (KR) 2001-02-07 EP disclosed
US-5430153-A Insecticides, fungicides KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1995-07-04 US disclosed
EP-0533882-A1 2-QUINOLINONE DERIVATIVES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1993-03-31 EP disclosed
WO-1992017452-A1 2-QUINOLINONE DERIVATIVES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1992-10-15 WO disclosed