SCHEMBL7809535

SCHEMBL7809535

CSOc1c(C(C)=O)c(=O)[nH]c2c(-c3ccccc3)cccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FEN1 P39748 1/20 0.42
KDM4E B2RXH2 4/20 0.41
TSHR P16473 2/20 0.36
ALDH1A1 P00352 2/20 0.36
LMNA P02545 2/20 0.36
GLA P06280 1/20 0.36
GAA P10253 1/20 0.36
HSD17B10 Q99714 1/20 0.36
HK2 P52789 1/20 0.36
SERPINE1 P05121 1/20 0.36
CDK4 P11802 4/20 0.36
CCND1 P24385 4/20 0.36
MCL1 Q07820 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MAPT P10636 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
HPGD P15428 1/20 0.34
CCNB2 O95067 1/20 0.34
CCNE2 O96020 1/20 0.34
CDK1 P06493 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7809500 0.83 KDM4E (0.45) KDM4ETSHRALDH1A1LMNAGAA
SCHEMBL7804026 0.81 RXFP1 (0.45) KDM4ELMNACDK1CCNB1TUBB4A
SCHEMBL7813789 0.81 FEN1 (0.39) FEN1KDM4EALDH1A1LMNASMN1; SMN2
SCHEMBL7809669 0.81 DAO (0.40) KDM4ETSHRALDH1A1LMNAHSD17B10
SCHEMBL7809532 0.81 FEN1 (0.40) FEN1KDM4ETSHRALDH1A1LMNA
SCHEMBL7817120 0.80 CAPN1 (0.44) KDM4EALDH1A1LMNAHSD17B10SMN1; SMN2
SCHEMBL497316 0.78 KDM4E (0.58) KDM4EALDH1A1LMNAGAAHSD17B10
SCHEMBL7811364 0.70 TUBB4A (0.39) FEN1KDM4ETSHRALDH1A1HSD17B10
SCHEMBL7811064 0.70 KDM4E (0.39) KDM4EALDH1A1GAAHSD17B10
SCHEMBL7812988 0.69 MEN1 (0.34) ALDH1A1MEN1NPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0533882-B1 2-QUINOLINONE DERIVATIVES, METHODS FOR PREPARING THE SAME AND FUNGICIDES AND INSECTICIDES INCLUDING THEM KOREA RES INST CHEM TECH (KR) 2001-02-07 EP disclosed
US-5430153-A Insecticides, fungicides KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1995-07-04 US disclosed