Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 5/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | CHUK | O15111 | 1/20 | 0.54 |
| ▸ | BTK | Q06187 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 9/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | CDC7 | O00311 | 1/20 | 0.50 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2313705 | 0.83 | IKBKB (0.77) | IKBKBCYP1A2CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL875389 | 0.82 | IKBKB (0.60) | IKBKBCYP1A2CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL29906389 | 0.82 | IKBKB (0.60) | IKBKBCYP1A2CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL5860808 | 0.82 | CCR1 (0.50) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL5195454 | 0.81 | IKBKB (0.55) | IKBKBCYP1A2CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL16426250 | 0.81 | IKBKB (0.55) | IKBKBCYP1A2CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL2044907 | 0.80 | IKBKB (0.77) | IKBKBCYP1A2CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL5192759 | 0.80 | IKBKB (0.55) | IKBKBCYP1A2CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL3081896 | 0.80 | MAPT (0.63) | IKBKBCYP1A2CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL611877 | 0.80 | CDC7 (0.77) | IKBKBCYP1A2CYP2C9CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9688653-B2 | Ethoxyphenyl thienyl compounds and methods for the treatment of bacterial infections | DUKE UNIVERSITY (US) | 2017-06-27 | — | — | US | disclosed |
| US-20150031658-A1 | ETHOXYPHENYL THIENYL COMPOUNDS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS | UNIV DUKE (US) | 2015-01-29 | — | — | US | disclosed |
| EP-0783501-B9 | PYRIMIDONE DERIVATIVES WITH ANTIFUNGAL ACTIVITY | URIACH & CIA SA J (ES) | 2001-07-25 | — | — | EP | disclosed |
| EP-0783501-B1 | PYRIMIDONE DERIVATIVES WITH ANTIFUNGAL ACTIVITY | URIACH & CIA SA J (ES) | 2001-01-10 | — | — | EP | disclosed |
| US-5807854-A | THERAPY FOR FUNGI INFECTIONS IN PLANTS, ANIMALS | J. URIAH & CIA. S.A. (ES) | 1998-09-15 | — | — | US | disclosed |
| EP-0783501-A1 | NEW PYRIMIDONE DERIVATIVES WITH ANTIFUNGAL ACTIVITY | J. URIACH & CIA. S.A. (ES) | 1997-07-16 | — | — | EP | disclosed |
| WO-1997005130-A1 | NEW PYRIMIDONE DERIVATIVES WITH ANTIFUNGAL ACTIVITY | J. URIACH & CIA. S.A. (ES) | 1997-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150031658-A1 | ETHOXYPHENYL THIENYL COMPOUNDS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS | GGPS1, FDPS, FNTA | IKBKB 1461/4885CYP1A2 4023/4885CYP2C9 4514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.