Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.53 |
| ▸ | CCR5 | P51681 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | GCGR | P47871 | 2/20 | 0.47 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7814084 | 0.96 | HRH1 (0.56) | HRH1HRH3S1PR1CCR5ALDH1A1 | |
| SCHEMBL7817613 | 0.90 | CCR5 (0.51) | HRH1HRH3S1PR1CCR5ALDH1A1 | |
| SCHEMBL7817573 | 0.89 | ALDH1A1 (0.59) | HRH1HRH3S1PR1CCR5ALDH1A1 | |
| SCHEMBL7813354 | 0.86 | CCR5 (0.51) | HRH1HRH3S1PR1CCR5ALDH1A1 | |
| SCHEMBL9011180 | 0.84 | CCR5 (0.55) | HRH1HRH3S1PR1CCR5ALDH1A1 | |
| SCHEMBL7804406 | 0.83 | S1PR1 (0.57) | HRH1HRH3S1PR1MEN1KMT2A | |
| SCHEMBL7804447 | 0.83 | ALDH1A1 (0.48) | CCR5ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL7804694 | 0.83 | ALDH1A1 (0.56) | HRH3ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9011078 | 0.83 | CCR5 (0.54) | HRH1HRH3S1PR1CCR5ALDH1A1 | |
| SCHEMBL27295602 | 0.83 | CCR5 (0.66) | CCR5ALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |