SCHEMBL7809751

SCHEMBL7809751

Nc1ccc(NCC(O)CO)c(-c2ccc[nH]2)c1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CDK2 P24941 3/20 0.33
PDE3B Q13370 1/20 0.31
PDE3A Q14432 1/20 0.31
CHEK1 O14757 1/20 0.31
CDK1 P06493 1/20 0.31
AR P10275 1/20 0.30
VDR P11473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7805919 0.88 CDK2 (0.36) CDK2
SCHEMBL7809613 0.81 CDK2 (0.47) CDK2
SCHEMBL6571461 0.80 CHEK1 (0.41) CHEK1CDK1
SCHEMBL6574847 0.79 PDE3B (0.37) PDE3BPDE3ACHEK1CDK1AR
SCHEMBL7805942 0.79 CDK2 (0.41) CDK2CHEK1CDK1
Hydrochloric Acid SCHEMBL6572537 0.79 CHEK1 (0.40) CHEK1CDK1
SCHEMBL6571859 0.79 KDM4E (0.37) CHEK1CDK1
SCHEMBL6570818 0.78 AR (0.33) PDE3BPDE3AARVDR
SCHEMBL6572042 0.78 PDE3B (0.34) PDE3BPDE3ACHEK1CDK1AR
SCHEMBL6570912 0.77 ALDH1A1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0943614-B1 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives WELLA AG (DE) 2001-12-12 EP disclosed
US-6042620-A FOR DYEING KERATIN FIBERS SUCH AS HAIR WELLA AG (DE) 2000-03-28 US disclosed
EP-0943614-A2 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives Wella Aktiengesellschaft (DE) 1999-09-22 EP disclosed