Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2950121 | 0.81 | VCAM1 (0.50) | GPR35TSHRVCAM1MEN1KMT2A | |
| SCHEMBL21957846 | 0.81 | VCAM1 (0.50) | GPR35TSHRVCAM1MEN1KMT2A | |
| SCHEMBL16979 | 0.81 | GPR35 (1.00) | GPR35TSHRHPGDTDP1ALDH1A1 | |
| SCHEMBL29516730 | 0.81 | GPR35 (1.00) | GPR35TSHRHPGDTDP1ALDH1A1 | |
| SCHEMBL18938545 | 0.79 | GPR35 (0.96) | GPR35TSHRHPGDTDP1ALDH1A1 | |
| Fluoride SCHEMBL8639543 | 0.79 | GPR35 (0.96) | GPR35TSHRHPGDTDP1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL4427722 | 0.79 | GPR35 (0.96) | GPR35TSHRHPGDTDP1ALDH1A1 | |
| SCHEMBL27287865 | 0.79 | GPR35 (0.96) | GPR35TSHRHPGDTDP1ALDH1A1 | |
| SCHEMBL5492558 | 0.79 | GPR35 (0.96) | GPR35TSHRHPGDTDP1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL30775489 | 0.79 | GPR35 (0.96) | GPR35TSHRHPGDTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2811828-A1 | ADJUVANT COMPOSITIONS | Syngenta Participations AG (CH) | 2014-12-17 | — | — | EP | disclosed |
| WO-2013110553-A1 | ADJUVANT COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-08-01 | — | — | WO | disclosed |
| EP-1119547-A1 | SUBSTITUTED PYRROLIDINONE, THIAZOLIDINONE OR OXAZOLIDINONE AS HERBICIDES | Syngenta Limited (GB) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000021928-A1 | SUBSTITUTED PYRROLIDINONE, THIAZOLIDINONE OR OXAZOLIDINONE AS HERBICIDES | SYNGENTA LIMITED (GB) | 2000-04-20 | — | — | WO | disclosed |