Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 8/20 | 0.56 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30199336 | 0.85 | CHRM2 (0.47) | PRCPSLC22A1GAARECQL | |
| SCHEMBL30199293 | 0.83 | ALDH1A1 (0.44) | PRCPSLC22A1GAATSHRNPSR1 | |
| SCHEMBL987517 | 0.81 | PRCP (0.51) | PRCPSLC22A1GAATSHRNPSR1 | |
| SCHEMBL30199123 | 0.80 | PRCP (0.44) | PRCPSLC22A1GAATSHRNPSR1 | |
| SCHEMBL30199729 | 0.79 | PRCP (0.39) | PRCPSLC22A1TSHRNPSR1 | |
| SCHEMBL28495268 | 0.78 | PRCP (0.47) | PRCPSLC22A1GAATSHRNPSR1 | |
| SCHEMBL8813918 | 0.78 | GID4 (0.49) | PRCPSLC22A1GAATSHRNPSR1 | |
| Acetonitrile SCHEMBL9306677 | 0.77 | CTSL (0.41) | PRCPSLC22A1CYP2C19 | |
| SCHEMBL10571581 | 0.76 | PRCP (0.44) | PRCPSLC22A1GAATSHRNPSR1 | |
| SCHEMBL10796144 | 0.76 | HTR2C (0.50) | PRCPSLC22A1GAACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107793356-A | A kind of salt derivative of tetrahydroisoquinoline and its preparation method and application of crystal | 上海医药工业研究院 | 2018-03-13 | — | — | CN | claimed |
| EP-1163225-A1 | COMPOUNDS AND METHODS FOR MODULATION OF ESTROGEN RECEPTORS | SIGNAL PHARMACEUTICALS, INC. (US) | 2001-12-19 | — | — | EP | disclosed |
| WO-2000055137-A1 | COMPOUNDS AND METHODS FOR MODULATION OF ESTROGEN RECEPTORS | SIGNAL PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |