Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10592999 | 0.82 | HPGDS (0.59) | NPC1RAB9AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL31074229 | 0.79 | CES2 (0.56) | NPC1RAB9AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL2760408 | 0.77 | HPGDS (0.69) | NPC1RAB9AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL28632150 | 0.77 | NPC1 (0.56) | NPC1RAB9AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL13767983 | 0.77 | NPC1 (0.56) | NPC1RAB9AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL7207262 | 0.75 | NPC1 (0.67) | NPC1RAB9AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL4460667 | 0.73 | ALDH1A1 (0.52) | NPC1RAB9AALDH1A1SMN1; SMN2HPGD | |
| Acetic Acid SCHEMBL11320089 | 0.73 | HPGDS (0.68) | NPC1RAB9AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL7207744 | 0.72 | NPC1 (0.61) | NPC1RAB9AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL15979662 | 0.72 | NPC1 (0.70) | NPC1RAB9AALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891345-B1 | NOVEL FURAN DIARYLMETHYLIDENE DERIVATIVES, METHOD FOR THEIR PREPARATION AND THERAPEUTICAL USES THEREOF | UNION PHARMA SCIENT APPL (FR) | 2001-08-16 | — | — | EP | disclosed |
| US-6180651-B1 | ANTIINFLAMMATORY AGENTS; ANALGESICS | BRISTOL-MYERS SQUIBB | 2001-01-30 | — | — | US | disclosed |
| WO-2000014082-A1 | DIARYLMETHYLIDENE FURAN DERIVATIVES AS DRUGS WITH ANTI-INFLAMMATORY, ANALGESIC AND CHEMOPREVENTIVE PROPERTIES | LABORATORIES UPSA (FR) | 2000-03-16 | — | — | WO | disclosed |
| EP-0891345-A1 | NOVEL FURAN DIARYLMETHYLIDENE DERIVATIVES, METHOD FOR THEIR PREPARATION AND THERAPEUTICAL USES THEREOF | LABORATOIRES UPSA (FR) | 1999-01-20 | — | — | EP | disclosed |
| US-5807873-A | Diarylmethylidenefuran derivatives and their uses in therapeutics | LABORATORIES UPSA (FR) | 1998-09-15 | — | — | US | disclosed |
| WO-1997037984-A1 | NOVEL FURAN DIARYLMETHYLIDENE DERIVATIVES, METHOD FOR THEIR PREPARATION AND THERAPEUTICAL USES THEREOF | LABORATOIRES UPSA (FR) | 1997-10-16 | — | — | WO | disclosed |
| US-4054682-A | COATINGS, PRINTING INKS | BASF AKTIENGESELLSCHAFT (DT) | 1977-10-18 | — | — | US | disclosed |