SCHEMBL7811281

SCHEMBL7811281

CC(=O)NC[C@H]1CN(c2ccc(N3CCC(=O)C3)c(F)c2)C(=O)O1

nearest known ligand 0.76

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOA P21397 6/20 0.76
MAOB P27338 6/20 0.76
PTGS1 P23219 2/20 0.76
SDHA P31040 2/20 0.76
LMNA P02545 1/20 0.76
CALML3 P27482 1/20 0.76
F10 P00742 6/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6851173 1.00 MAOA (0.76) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6735636 0.94 MAOA (0.73) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6735633 0.94 MAOA (0.73) MAOAMAOBPTGS1SDHALMNA
SCHEMBL3185881 0.94 MAOA (0.82) MAOAMAOBPTGS1SDHALMNA
SCHEMBL3568166 0.94 MAOA (0.82) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6615781 0.92 MAOA (0.78) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6615783 0.92 MAOA (0.78) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6987847 0.91 MAOA (0.76) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6987852 0.91 MAOA (0.76) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7818282 0.89 MAOA (0.71) MAOAMAOBPTGS1SDHALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5883093-A TREATING MICROBIAL INFECTIONS IN WARM BLOODED ANIMALS, INCLUDING HUMANS PHARMACIA & UPJOHN COMPANY (US) 1999-03-16 US claimed
EP-0788498-B1 PHENYLOXAZOLIDINONE ANTIMICROBIALS UPJOHN CO (US) 2001-08-16 EP disclosed
US-5883093-A TREATING MICROBIAL INFECTIONS IN WARM BLOODED ANIMALS, INCLUDING HUMANS PHARMACIA & UPJOHN COMPANY (US) 1999-03-16 US disclosed
EP-0788498-A1 PHENYLOXAZOLIDINONE ANTIMICROBIALS PHARMACIA & UPJOHN COMPANY (US) 1997-08-13 EP disclosed
WO-1996013502-A1 PHENYLOXAZOLIDINONE ANTIMICROBIALS PHARMACIA & UPJOHN COMPANY (US) 1996-05-09 WO disclosed