Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7809429 | 0.89 | SIGMAR1 (0.42) | KMOMEN1KMT2A | |
| SCHEMBL7809519 | 0.86 | MEN1 (0.45) | HPGDMEN1KMT2A | |
| SCHEMBL7815213 | 0.85 | HPGD (0.48) | HPGDTACR1SLC6A4CA12CA9 | |
| SCHEMBL6969737 | 0.85 | ALDH1A1 (0.44) | SLC6A4KMOMEN1KMT2ASLC6A2 | |
| SCHEMBL7807793 | 0.84 | TACR1 (0.42) | TACR1HSP90AA1MEN1KMT2A | |
| SCHEMBL6962001 | 0.84 | MEN1 (0.49) | SLC6A4MEN1KMT2ANPC1TDP1 | |
| SCHEMBL8801314 | 0.82 | HPGD (0.45) | HPGDSLC6A4CA12CA9HSP90AA1 | |
| SCHEMBL8801310 | 0.82 | HPGD (0.45) | HPGDSLC6A4CA12CA9HSP90AA1 | |
| SCHEMBL7803017 | 0.81 | KDM4E (0.43) | HSP90AA1MEN1KMT2A | |
| SCHEMBL9119210 | 0.74 | HPGD (0.44) | HPGDSLC6A4CA12CA9HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773929-B1 | PIPERIDINE DERIVATIVES AS NEUROKININ ANTAGONISTS | SCHERING CORP (US) | 2001-10-31 | — | — | EP | disclosed |
| US-5654316-A | Piperidine derivatives as neurokinin antagonists | SCHERING CORPORATION (US) | 1997-08-05 | — | — | US | disclosed |