Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.48 |
| ▸ | PARP14 | Q460N5 | 3/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811526 | 0.91 | PARP10 (0.53) | PARP10PARP14HSD11B1MAPTALDH1A1 | |
| SCHEMBL7809992 | 0.87 | ALDH1A1 (0.52) | PARP10HSD11B1L3MBTL1MAPTALDH1A1 | |
| SCHEMBL7811616 | 0.87 | NPC1 (0.52) | PARP10PARP14HSD11B1NPC1HPGD | |
| SCHEMBL7810089 | 0.82 | MAPT (0.53) | PARP10PARP14MAPTNPC1DRD2 | |
| SCHEMBL7811596 | 0.82 | NPC1 (0.51) | PARP10PARP14HSD11B1NPC1LMNA | |
| SCHEMBL7817613 | 0.80 | CCR5 (0.51) | MAPTALDH1A1NPC1KMT2ATP53 | |
| SCHEMBL7810100 | 0.79 | BCL9 (0.56) | PARP10PARP14HSD11B1CA12CA1 | |
| SCHEMBL7804406 | 0.79 | S1PR1 (0.57) | PARP10PARP14HSD11B1MAPTCA12 | |
| SCHEMBL7811675 | 0.79 | KMT2A (0.58) | HSD11B1L3MBTL1MAPTALDH1A1CYP1A2 | |
| SCHEMBL7811446 | 0.78 | PARP10 (0.48) | PARP10PARP14ALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |