Sugi Predict

Sugi Predict / Compounds / SCHEMBL781168

SCHEMBL781168

SCHEMBL781168

c1ccc(-n2c3ccccc3c3cc(-c4cccc5c4sc4ccccc45)ccc32)c(-c2cc3ccccc3c3ccccc23)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 1/20 0.48
▸ PRKDC P78527 6/20 0.40
▸ PARP14 Q460N5 1/20 0.33
▸ PIK3CD O00329 2/20 0.32
▸ PIK3CB P42338 2/20 0.32
▸ BRD4 O60885 1/20 0.32
▸ PIK3CA P42336 1/20 0.32
▸ MTOR P42345 1/20 0.32
▸ PIK3CG P48736 1/20 0.32
▸ KCNH2 Q12809 1/20 0.32
▸ BRDT Q58F21 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.31
▸ HPGD P15428 1/20 0.31
▸ TSHR P16473 1/20 0.31
▸ MAPK1 P28482 1/20 0.31
▸ CASP1 P29466 1/20 0.31
▸ HIF1A Q16665 1/20 0.31
▸ HSD17B10 Q99714 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31
▸ TNKS O95271 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13829709 0.92 ALOX5 (0.56) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL780768 0.91 ALOX5 (0.50) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL781106 0.89 ALOX5 (0.48) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL781056 0.89 ALOX5 (0.52) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL780587 0.89 ALOX5 (0.52) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL10165697 0.89 ALOX5 (0.52) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL13830018 0.88 ALOX5 (0.57) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL781165 0.88 ALOX5 (0.47) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL15745736 0.88 ALOX5 (0.49) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL17248400 0.87 ALOX5 (0.56) ALOX5PRKDCPARP14PIK3CDPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8642782-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 — — US disclosed
US-8642782-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 — — US disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 — — US disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SLC39A3, SULT1A1, NUTF2 ALOX5 1162/4885PRKDC 3567/4885PARP14 3228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.