SCHEMBL10165697

SCHEMBL10165697

c1ccc2c(-n3c4ccccc4c4cc(-c5cccc6c5sc5ccccc56)ccc43)cccc2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.52
PRKDC P78527 6/20 0.42
POLB P06746 1/20 0.38
PARP14 Q460N5 1/20 0.36
PIK3CD O00329 2/20 0.34
PIK3CB P42338 2/20 0.34
BRD4 O60885 1/20 0.34
PIK3CA P42336 1/20 0.34
MTOR P42345 1/20 0.34
PIK3CG P48736 1/20 0.34
KCNH2 Q12809 1/20 0.34
BRDT Q58F21 1/20 0.34
GSK3A P49840 1/20 0.33
GSK3B P49841 1/20 0.33
TNKS O95271 1/20 0.33
TNKS2 Q9H2K2 1/20 0.33
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
MAPT P10636 1/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10165740 0.95 ALOX5 (0.47) ALOX5PRKDCPOLBPARP14PIK3CD
SCHEMBL18779526 0.93 ALOX5 (0.46) ALOX5PRKDCPOLBPARP14PIK3CD
SCHEMBL18779558 0.93 ALOX5 (0.46) ALOX5PRKDCPOLBPARP14PIK3CD
SCHEMBL10165722 0.93 ALOX5 (0.52) ALOX5PRKDCPOLBPARP14PIK3CD
SCHEMBL13830018 0.92 ALOX5 (0.57) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL22672197 0.92 ALOX5 (0.46) ALOX5PRKDCPOLBPARP14PIK3CD
SCHEMBL15745736 0.92 ALOX5 (0.49) ALOX5PRKDCPOLBPARP14PIK3CD
SCHEMBL17248395 0.92 ALOX5 (0.48) ALOX5PRKDCPOLBPARP14PIK3CD
SCHEMBL23468825 0.91 ALOX5 (0.41) ALOX5PRKDCPOLBGSK3AGSK3B
SCHEMBL17248400 0.91 ALOX5 (0.56) ALOX5PRKDCPARP14PIK3CDPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10014480-B2 Heterocyclic compounds and organic electroluminescent devices using the same E-RAY OPTOELECTRONICS TECHNOLOGY CO., LTD. (TW) 2018-07-03 US disclosed
US-10014480-B2 Heterocyclic compounds and organic electroluminescent devices using the same E-RAY OPTOELECTRONICS TECHNOLOGY CO., LTD. (TW) 2018-07-03 US disclosed
US-20160133848-A1 HETEROCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME E-RAY OPTOELECTRONICS TECHONOLOGY CO., LTD. (TW) 2016-05-12 US disclosed
US-20160133848-A1 HETEROCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME E-RAY OPTOELECTRONICS TECHONOLOGY CO., LTD. (TW) 2016-05-12 US disclosed
US-9133173-B2 Carbazole compound, material for light-emitting element, organic semiconductor material, light-emitting element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-09-15 US disclosed
US-9133173-B2 Carbazole compound, material for light-emitting element, organic semiconductor material, light-emitting element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-09-15 US disclosed
US-20120091887-A1 Carbazole Compound, Material for Light-Emitting Element, Organic Semiconductor Material, Light-Emitting Element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-04-19 US disclosed
US-20120091887-A1 Carbazole Compound, Material for Light-Emitting Element, Organic Semiconductor Material, Light-Emitting Element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160133848-A1 HETEROCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME LEF1, HVCN1, KCNC1 ALOX5 1064/4885PRKDC 4516/4885POLB 2931/4885
US-20120091887-A1 Carbazole Compound, Material for Light-Emitting Element, Organic Semiconductor Material, Light-Emitting Element NUTF2, BRI3BP, CLINT1 ALOX5 1931/4885PRKDC 2968/4885POLB 3517/4885
US-10014480-B2 Heterocyclic compounds and organic electroluminescent devices using the same LEF1, HVCN1, KCNC1 ALOX5 1064/4885PRKDC 4516/4885POLB 2931/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.