Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11648181 | 0.84 | NPC1 (0.53) | MAPTALDH1A1KDM4ELMNANPC1 | |
| SCHEMBL457878 | 0.79 | — | — | |
| Hydrogen Sulfide SCHEMBL28274988 | 0.77 | IDO1 (0.52) | MAPTALDH1A1KDM4ELMNANPC1 | |
| Hydrochloric Acid SCHEMBL11322195 | 0.77 | IDO1 (0.52) | MAPTALDH1A1KDM4ELMNANPC1 | |
| Hydrochloric Acid SCHEMBL11320051 | 0.77 | IDO1 (0.52) | MAPTALDH1A1KDM4ELMNANPC1 | |
| SCHEMBL5792178 | 0.75 | NPC1 (0.43) | MAPTALDH1A1KDM4ELMNANPC1 | |
| SCHEMBL9396097 | 0.75 | GABRA1 (0.41) | MAPTALDH1A1KDM4ELMNANPC1 | |
| SCHEMBL24289348 | 0.74 | MAPT (0.48) | MAPTALDH1A1KDM4ELMNANPC1 | |
| SCHEMBL6842557 | 0.74 | — | — | |
| SCHEMBL22169178 | 0.73 | ALDH1A1 (0.57) | MAPTALDH1A1KDM4ELMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896466-B1 | N-LINKED HETEROCYCLIC ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS | BRISTOL MYERS SQUIBB CO (US) | 2011-04-13 | — | — | EP | disclosed |
| US-20010005914-A1 | OXIDATION DYES | ANDREAS J. BITTNER | 2001-07-05 | — | — | US | disclosed |
| US-6024768-A | HUMAN HAIR COLORING; HAIR CONDITIONERS | HANS SCHWARZKOPF GMBH & CO. KG (DE) | 2000-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010005914-A1 | OXIDATION DYES | AOC1, CBR3, KRT18 | MAPT 3633/4885ALDH1A1 26/4885KDM4E 606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.