Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6838898 | 0.89 | HTT (0.38) | TAS1R3TAS1R1TAS1R2KMT2AHPGD | |
| SCHEMBL6838601 | 0.86 | ALDH1A1 (0.32) | TAS1R3TAS1R1TAS1R2KMT2AKDM4E | |
| SCHEMBL9883885 | 0.86 | KDM4E (0.42) | TAS1R3TAS1R1TAS1R2KMT2AHPGD | |
| SCHEMBL3256843 | 0.85 | ALDH1A1 (0.31) | SMN1; SMN2ALDH1A1MAPK1POLB | |
| SCHEMBL7479979 | 0.82 | HTT (0.34) | KMT2AHPGDL3MBTL1LMNAALDH1A1 | |
| SCHEMBL3676493 | 0.82 | SMN1; SMN2 (0.33) | KMT2AHPGDMEN1SMN1; SMN2LMNA | |
| SCHEMBL5772246 | 0.80 | NPC1 (0.32) | HPGDSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL16485238 | 0.79 | KDM4E (0.32) | KDM4EL3MBTL1 | |
| SCHEMBL2461457 | 0.79 | SMURF2 (0.31) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL6308979 | 0.78 | KMT2A (0.38) | KMT2AKDM4EMEN1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9868714-B2 | Pyrone compounds and herbicides comprising the same | SUMITOMO CHEMICAL COMPANY (JP) | 2018-01-16 | — | — | US | disclosed |
| US-9868714-B2 | Pyrone compounds and herbicides comprising the same | SUMITOMO CHEMICAL COMPANY (JP) | 2018-01-16 | — | — | US | disclosed |
| US-9868714-B2 | Pyrone compounds and herbicides comprising the same | SUMITOMO CHEMICAL COMPANY (JP) | 2018-01-16 | — | — | US | disclosed |
| CN-104854102-B | Pyranone compounds and the herbicide comprising pyranone compounds | 住友化学株式会社 | 2017-09-01 | — | — | CN | disclosed |
| EP-2723723-B1 | N-OXY PYRAZOLO-TRIAZEPINE-DIONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-02-01 | — | — | EP | disclosed |
| EP-2906557-B1 | PYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | SUMITOMO CHEMICAL CO (JP) | 2016-11-30 | — | — | EP | disclosed |
| EP-2906557-B1 | PYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | SUMITOMO CHEMICAL CO (JP) | 2016-11-30 | — | — | EP | disclosed |
| US-9282743-B2 | Chemical compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-15 | — | — | US | disclosed |
| US-20150274691-A1 | PYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2015-10-01 | — | — | US | disclosed |
| US-20150274691-A1 | PYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2015-10-01 | — | — | US | disclosed |
| WO-1997016436-A1 | 3-ARYL-5-HALOGEN-PYRONE DERIVATIVES AS PEST CONTROL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-05-09 | — | — | WO | disclosed |
| EP-0508126-B1 | 3-Hydroxy-4-aryl-5-oxo-pyrazolin derivatives | BAYER AG (DE) | 1997-05-02 | — | — | EP | disclosed |
| US-5565450-A | PESTICIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-10-15 | — | — | US | disclosed |
| US-5474974-A | Insecticide, pesticide, nematocide, miticide and herbicide | BAYER AKTIENGESELLSCHAFT (DE) | 1995-12-12 | — | — | US | disclosed |
| US-5393729-A | Pesticides, fungicides, herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-02-28 | — | — | US | disclosed |
| US-5358924-A | Pesticides, miticides, insecticides and herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-10-25 | — | — | US | disclosed |
| US-5332720-A | 3-hydroxy-4-aryl-5-oxo-pyrazoline derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1994-07-26 | — | — | US | disclosed |
| WO-1994014785-A1 | 5-ARYL-1,3-THIAZINE DERIVATIVES, MANUFACTURE THEREOF AND USE AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1994-07-07 | — | — | WO | disclosed |
| EP-0588137-A1 | 3-Aryl-2-pyranone derivatives | BAYER AG (DE) | 1994-03-23 | — | — | EP | disclosed |
| EP-0508126-A1 | 3-Hydroxy-4-aryl-5-oxo-pyrazolin derivatives | BAYER AG (DE) | 1992-10-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150274691-A1 | PYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | CBR3, NOTUM, DDT | TAS1R3 1063/4885TAS1R1 737/4885TAS1R2 1004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.