Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SPR | P35270 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6838898 | 0.86 | HTT (0.38) | KMT2ALMNAMAPTNPC1RAB9A | |
| SCHEMBL7479979 | 0.80 | HTT (0.34) | KMT2ALMNAMAPTALDH1A1POLB | |
| SCHEMBL812041 | 0.79 | AKR1C2 (0.44) | KMT2ASMN1; SMN2KDM4EAKR1C3AKR1C2 | |
| SCHEMBL7811949 | 0.78 | TAS1R3 (0.35) | KMT2ALMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6838601 | 0.77 | ALDH1A1 (0.32) | KMT2ASMN1; SMN2ALDH1A1MAPK1KDM4E | |
| SCHEMBL3256843 | 0.75 | ALDH1A1 (0.31) | SMN1; SMN2ALDH1A1MAPK1POLB | |
| SCHEMBL5772246 | 0.74 | NPC1 (0.32) | LMNANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL12233904 | 0.74 | KMT2A (0.43) | KMT2ALMNAMAPTABCB1NPC1 | |
| SCHEMBL3765067 | 0.74 | SMN1; SMN2 (0.52) | KMT2ALMNAMAPTMRGPRX4SMN1; SMN2 | |
| SCHEMBL3676493 | 0.72 | SMN1; SMN2 (0.33) | KMT2ALMNAMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050164885-A1 | Alkyl dihalogenated phenyl-substituted ketoenols useful as pesticides and herbicides | BAYER AG (DE) | 2005-07-28 | — | — | US | disclosed |
| US-6858741-B2 | Alkyl-dihalogenated phenyl-substituted ketoenols useful as pesticides and herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2005-02-22 | — | — | US | disclosed |
| US-20030199572-A1 | Alkyl-dihalogenophenyl-substituted ketoenols | LIEB FOLKER (DE) | 2003-10-23 | — | — | US | disclosed |
| EP-0825982-B1 | ALKYL DIHALOGENATED PHENYL-SUBSTITUTED KETOENOLS USEFUL AS PESTICIDES AND HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2002-11-27 | — | — | EP | disclosed |
| US-6380246-B1 | FOR COMBATING PESTS AND WEEDS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-04-30 | — | — | US | disclosed |
| US-6316486-B1 | FOR COMBATING PESTS AND WEED | BAYER AKTIENGESELLSCHAFT (DE) | 2001-11-13 | — | — | US | disclosed |
| EP-0825982-A1 | ALKYL DIHALOGENATED PHENYL-SUBSTITUTED KETOENOLS USEFUL AS PESTICIDES AND HERBICIDES | BAYER AG (DE) | 1998-03-04 | — | — | EP | disclosed |
| WO-1996035664-A1 | ALKYL DIHALOGENATED PHENYL-SUBSTITUTED KETOENOLS USEFUL AS PESTICIDES AND HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050164885-A1 | Alkyl dihalogenated phenyl-substituted ketoenols useful as pesticides and herbicides | DDT, CYP8B1, PAOX | KMT2A 511/4885LMNA 3005/4885MAPT 4471/4885 |
| US-20030199572-A1 | Alkyl-dihalogenophenyl-substituted ketoenols | CYP2E1, CYP8B1, CYP24A1 | KMT2A 761/4885LMNA 2385/4885MAPT 4856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.