SCHEMBL7479979

SCHEMBL7479979

Cc1cc(Cl)c(C(=C=O)C(=O)Cl)c(Cl)c1

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.34
TSHR P16473 1/20 0.34
ALDH1A1 P00352 2/20 0.33
MAPT P10636 2/20 0.33
KMT2A Q03164 3/20 0.33
LMNA P02545 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
POLB P06746 1/20 0.31
HPGD P15428 1/20 0.31
GPR35 Q9HC97 1/20 0.31
TPMT P51580 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6838898 0.91 HTT (0.38) HTTTSHRALDH1A1MAPTKMT2A
SCHEMBL7811949 0.82 TAS1R3 (0.35) HTTTSHRALDH1A1MAPTKMT2A
SCHEMBL6308979 0.80 KMT2A (0.38) HTTTSHRALDH1A1MAPTKMT2A
SCHEMBL6838601 0.77 ALDH1A1 (0.32) ALDH1A1KMT2APOLB
SCHEMBL812041 0.76 AKR1C2 (0.44) KMT2A
SCHEMBL7270831 0.74 ALDH1A1 (0.52) HTTTSHRALDH1A1MAPTKMT2A
SCHEMBL5772246 0.74 NPC1 (0.32) ALDH1A1LMNAHPGD
SCHEMBL6838901 0.74 HTT (0.36) HTTTSHRALDH1A1MAPTKMT2A
SCHEMBL9883885 0.74 KDM4E (0.42) TSHRALDH1A1MAPTKMT2ALMNA
SCHEMBL14432141 0.72 GPR27 (0.36) HTTTSHRALDH1A1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0825982-B1 ALKYL DIHALOGENATED PHENYL-SUBSTITUTED KETOENOLS USEFUL AS PESTICIDES AND HERBICIDES BAYER CROPSCIENCE AG (DE) 2002-11-27 EP disclosed
EP-0825982-A1 ALKYL DIHALOGENATED PHENYL-SUBSTITUTED KETOENOLS USEFUL AS PESTICIDES AND HERBICIDES BAYER AG (DE) 1998-03-04 EP disclosed
WO-1996035664-A1 ALKYL DIHALOGENATED PHENYL-SUBSTITUTED KETOENOLS USEFUL AS PESTICIDES AND HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1996-11-14 WO disclosed