Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7821137 | 0.80 | KDM4E (0.34) | KDM4EALDH1A1HPGD | |
| SCHEMBL7811661 | 0.66 | KDM4E (0.33) | KDM4EALDH1A1HPGD | |
| SCHEMBL7811684 | 0.64 | HTT (0.31) | — | |
| SCHEMBL28724933 | 0.56 | ABCC8 (0.40) | KDM4EMEN1ALDH1A1POLBMAPT | |
| SCHEMBL7820058 | 0.50 | KDM4E (0.38) | KDM4EUSP2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL27413816 | 0.49 | AR (0.41) | KDM4EALDH1A1HPGD | |
| SCHEMBL9328654 | 0.49 | MEN1 (0.33) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL18212328 | 0.49 | IMPDH2 (0.37) | KDM4EMEN1ALDH1A1POLBMAPT | |
| SCHEMBL13163178 | 0.49 | DHODH (0.49) | KDM4EALDH1A1POLBMAPTHPGD | |
| SCHEMBL10619225 | 0.48 | LMNA (0.32) | KDM4EMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271392-B1 | Intermediates useful for the synthesis of 1-arylpyrrole pesticides | RHONE-POULENC INC. | 2001-08-07 | — | — | US | claimed |
| EP-0708090-A1 | Intermediates useful for the synthesis of pesticides | RHONE-POULENC AGROCHIMIE (FR) | 1996-04-24 | — | — | EP | claimed |
| US-6271392-B1 | Intermediates useful for the synthesis of 1-arylpyrrole pesticides | RHONE-POULENC INC. | 2001-08-07 | — | — | US | disclosed |
| EP-0708090-A1 | Intermediates useful for the synthesis of pesticides | RHONE-POULENC AGROCHIMIE (FR) | 1996-04-24 | — | — | EP | disclosed |