SCHEMBL781236

SCHEMBL781236

c1ccc(-c2cc(-c3ccccc3)c3oc4c(-c5ccc6c(c5)c5cc(-c7cc(-c8ccccc8)cc8c7oc7c(-c9ccccc9)cc(-c9ccccc9)cc78)ccc5n6-c5cccc(-c6ccc7c8ccccc8c8ccccc8c7c6)c5)cc(-c5ccccc5)cc4c3c2)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 5/20 0.33
KDM4E B2RXH2 3/20 0.33
ATM Q13315 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PLA2G2A P14555 3/20 0.32
PLA2G4A P47712 3/20 0.32
PDE10A Q9Y233 1/20 0.32
ALDH1A1 P00352 5/20 0.32
TSHR P16473 2/20 0.32
HSD17B10 Q99714 2/20 0.32
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
BRCA1 P38398 1/20 0.32
KMT2A Q03164 1/20 0.32
FAAH O00519 1/20 0.31
HSP90AA1 P07900 1/20 0.31
PKM P14618 1/20 0.31
HTT P42858 1/20 0.31
MGLL Q99685 1/20 0.31
PLA2G10 O15496 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL781141 0.98 ATM (0.38) PRKDCKDM4EATML3MBTL1PLA2G2A
SCHEMBL781061 0.93 ATM (0.38) PRKDCKDM4EATML3MBTL1PLA2G2A
SCHEMBL781297 0.93 PRKDC (0.33) PRKDCKDM4EATML3MBTL1PLA2G2A
SCHEMBL781263 0.93 EDNRB (0.32) PRKDCKDM4EATML3MBTL1PLA2G2A
SCHEMBL781213 0.93 KDM4E (0.35) PRKDCKDM4EATML3MBTL1PLA2G2A
SCHEMBL780981 0.92 PDE10A (0.32) PRKDCKDM4EATML3MBTL1PLA2G2A
SCHEMBL781452 0.92 PLA2G2A (0.35) PRKDCKDM4EATML3MBTL1PLA2G2A
SCHEMBL781515 0.91 KDM4E (0.40) PRKDCKDM4EATML3MBTL1PLA2G2A
SCHEMBL781169 0.91 KDM4E (0.33) PRKDCKDM4EATML3MBTL1PDE10A
SCHEMBL780904 0.91 KDM4E (0.36) KDM4EATML3MBTL1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160380211-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-12-29 US disclosed
US-9450188-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-20 US disclosed
US-9450188-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-20 US disclosed
US-20140145175-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-05-29 US disclosed
US-20140145175-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-05-29 US disclosed
US-8642782-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 US disclosed
US-8642782-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 US disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 US disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160380211-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SLC39A3, SULT1A1, NUTF2 PRKDC 3567/4885KDM4E 3917/4885ATM 2271/4885
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SLC39A3, SULT1A1, NUTF2 PRKDC 3567/4885KDM4E 3917/4885ATM 2271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.