Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 9/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7812186 | 0.76 | SLC6A9 (0.47) | KCNH2SLC6A9KDM4EMEN1MAPT | |
| SCHEMBL27372901 | 0.74 | SLC6A9 (0.44) | KCNH2SLC6A9KDM4EMEN1MAPT | |
| SCHEMBL7813263 | 0.74 | SLC6A9 (0.45) | KCNH2SLC6A9KDM4EMEN1MAPT | |
| SCHEMBL7803889 | 0.73 | SLC6A9 (0.45) | KCNH2SLC6A9KDM4EMEN1MAPT | |
| SCHEMBL7812976 | 0.71 | CA12 (0.46) | KCNH2SLC6A9 | |
| SCHEMBL27408116 | 0.69 | MAPK14 (0.36) | F10HRH3DRD2SLC6A4F2 | |
| SCHEMBL7808562 | 0.68 | HTR1A (0.61) | KCNH2SLC6A9HTR1BDRD2 | |
| SCHEMBL7803556 | 0.67 | SLC6A9 (0.40) | KCNH2SLC6A9MEN1MAPTKMT2A | |
| SCHEMBL8188389 | 0.66 | HTR1A (0.39) | KCNH2SLC6A9MAPTHTR1BDRD2 | |
| SCHEMBL7810698 | 0.66 | DRD2 (0.39) | KCNH2SLC6A9KDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767782-B1 | ARYL AND HETEROARYL ALKOXYNAPHTHALENE DERIVATIVES | PFIZER (US) | 2001-10-31 | — | — | EP | disclosed |
| US-6166020-A | Aryl and heteroaryl alkoxynaphthalene derivatives | PFIZER INC. (US) | 2000-12-26 | — | — | US | disclosed |
| EP-0767782-A1 | ARYL AND HETEROARYL ALKOXYNAPHTHALENE DERIVATIVES | PFIZER INC. (US) | 1997-04-16 | — | — | EP | disclosed |
| WO-1996000720-A1 | ARYL AND HETEROARYL ALKOXYNAPHTHALENE DERIVATIVES | PFIZER INC. (US) | 1996-01-11 | — | — | WO | disclosed |