Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7821017 | 0.82 | HDAC4 (0.54) | LMNAHDAC4HDAC8HSP90AA1HSP90AB1 | |
| SCHEMBL7652640 | 0.82 | CHEK1 (0.46) | CHEK1LMNAALDH1A1BRD4HDAC4 | |
| SCHEMBL2020140 | 0.79 | ABL1 (0.59) | LMNAALDH1A1BRD4HDAC4HDAC8 | |
| SCHEMBL7308295 | 0.76 | CHEK1 (0.41) | CHEK1LMNAALDH1A1BRD4HDAC4 | |
| SCHEMBL3455245 | 0.76 | ABL1 (0.60) | LMNAALDH1A1BRD4MAOBKDM4E | |
| SCHEMBL13211663 | 0.76 | ABL1 (0.60) | LMNAALDH1A1BRD4HDAC4HDAC8 | |
| SCHEMBL562949 | 0.75 | ALDH1A1 (0.44) | ALDH1A1HDAC4HDAC8HSD17B10CYP2A6 | |
| SCHEMBL3362978 | 0.75 | HDAC4 (0.62) | ALDH1A1BRD4HDAC4HDAC8HSD17B10 | |
| SCHEMBL12459745 | 0.74 | HDAC4 (0.56) | LMNAALDH1A1HDAC4HDAC8SERPINE1 | |
| SCHEMBL8887143 | 0.74 | GAA (0.59) | LMNAALDH1A1BRD4HDAC4HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |