Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2079237 | 0.90 | AKR1C1 (0.65) | AKR1C1ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL30487797 | 0.90 | AKR1C1 (0.65) | AKR1C1ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL3219884 | 0.88 | AKR1C1 (0.62) | AKR1C1ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL435932 | 0.88 | AKR1C1 (0.62) | AKR1C1ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL2535205 | 0.87 | AKR1C1 (0.59) | AKR1C1ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL301111 | 0.83 | AKR1C1 (0.53) | AKR1C1AKR1C3AKR1C2PSEN1PSEN2 | |
| SCHEMBL7813491 | 0.80 | LMNA (0.47) | AKR1C1ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL4811216 | 0.78 | P2RX7 (0.48) | AKR1C1ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL5768673 | 0.77 | AKR1C1 (0.46) | AKR1C1AKR1C3AKR1C2APPCYP3A4 | |
| SCHEMBL1626768 | 0.77 | ALDH1A1 (0.48) | AKR1C1ALDH1A1LMNATSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |