Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAG1 | P54619 | 1/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CDC25B | P30305 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.32 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.32 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.32 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.32 |
| ▸ | CDC25A | P30304 | 1/20 | 0.32 |
| ▸ | CDC25C | P30307 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25745 | 0.85 | CA12 (0.44) | PRKAG1PRKAA1PRKAB1TTRCYP1A2 | |
| SCHEMBL29355645 | 0.85 | CA12 (0.44) | PRKAG1PRKAA1PRKAB1TTRCYP1A2 | |
| SCHEMBL29358898 | 0.85 | CA12 (0.44) | PRKAG1PRKAA1PRKAB1TTRCYP1A2 | |
| SCHEMBL7813629 | 0.84 | PRKAG1 (0.34) | PRKAG1PRKAA1PRKAB1CA12CA9 | |
| SCHEMBL22793508 | 0.76 | TTR (0.43) | PRKAG1PRKAA1PRKAB1TTRCYP1A2 | |
| SCHEMBL134374 | 0.75 | CA12 (0.47) | PRKAG1PRKAA1PRKAB1TTRCYP1A2 | |
| SCHEMBL15962384 | 0.75 | TTR (0.43) | PRKAG1PRKAA1PRKAB1TTRCYP1A2 | |
| SCHEMBL21347987 | 0.74 | CA12 (0.47) | TTRCYP1A2CA12CA9CA4 | |
| SCHEMBL21347989 | 0.74 | CA12 (0.47) | PRKAG1PRKAA1PRKAB1TTRCYP1A2 | |
| SCHEMBL9626308 | 0.74 | CA12 (0.44) | PRKAG1PRKAA1PRKAB1TTRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |