Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7817420 | 0.91 | ALDH1A1 (0.55) | MAPTLMNATSHRMAPK1USP2 | |
| SCHEMBL7811730 | 0.91 | LMNA (0.50) | MAPTLMNATSHRMAPK1USP2 | |
| SCHEMBL7813608 | 0.90 | MAPT (0.57) | MAPTLMNATSHRALDH1A1HTT | |
| SCHEMBL7810031 | 0.90 | MAPT (0.49) | MAPTLMNATSHRMAPK1USP2 | |
| SCHEMBL7811456 | 0.90 | MAPT (0.49) | MAPTLMNATSHRMAPK1USP2 | |
| SCHEMBL7814074 | 0.90 | SMN1; SMN2 (0.53) | MAPTLMNATSHRMAPK1POLB | |
| SCHEMBL7814066 | 0.90 | ALDH1A1 (0.54) | MAPTLMNATSHRMAPK1USP2 | |
| SCHEMBL7811649 | 0.87 | ALDH1A1 (0.72) | MAPTMAPK1ALDH1A1HTTMEN1 | |
| SCHEMBL7813961 | 0.87 | KMT2A (0.51) | MAPTLMNATSHRMAPK1POLB | |
| SCHEMBL7813616 | 0.87 | ALDH1A1 (0.46) | MAPTLMNATSHRMAPK1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |