Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KHK | P50053 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.45 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7813660 | 0.91 | MAPT (0.56) | ALDH1A1SMN1; SMN2USP2MAPK1MAPT | |
| SCHEMBL7811649 | 0.89 | ALDH1A1 (0.72) | ALDH1A1GAASMN1; SMN2MAPK1MAPT | |
| SCHEMBL7811730 | 0.89 | LMNA (0.50) | ALDH1A1SMN1; SMN2USP2MAPK1MAPT | |
| SCHEMBL7814066 | 0.88 | ALDH1A1 (0.54) | ALDH1A1GAASMN1; SMN2USP2MAPK1 | |
| SCHEMBL7813608 | 0.88 | MAPT (0.57) | ALDH1A1SMN1; SMN2AKR1C3MAPTLMNA | |
| SCHEMBL7814074 | 0.88 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2MAPK1MAPTLMNA | |
| SCHEMBL7811456 | 0.88 | MAPT (0.49) | ALDH1A1SMN1; SMN2USP2MAPK1MAPT | |
| SCHEMBL7810031 | 0.88 | MAPT (0.49) | ALDH1A1GAASMN1; SMN2USP2MAPK1 | |
| SCHEMBL7813961 | 0.87 | KMT2A (0.51) | ALDH1A1GAASMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL7813616 | 0.85 | ALDH1A1 (0.46) | ALDH1A1GAASMN1; SMN2USP2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |