Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6648261 | 0.85 | MAPT (0.48) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL6648266 | 0.85 | MAPT (0.48) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL5264598 | 0.84 | MAPT (0.47) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL5264594 | 0.84 | MAPT (0.47) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL7814155 | 0.81 | PDE10A (0.46) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL6369459 | 0.80 | PDE10A (0.49) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL3769047 | 0.80 | PDE10A (0.51) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL8566533 | 0.78 | ALDH1A1 (0.53) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL15709862 | 0.77 | LMNA (0.61) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL10970697 | 0.76 | ALDH1A1 (0.56) | MEN1KMT2ARAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |