Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6648266 | 0.85 | MAPT (0.48) | PDE10APOLBLMNAALDH1A1MAPT | |
| SCHEMBL6648261 | 0.85 | MAPT (0.48) | PDE10APOLBLMNAALDH1A1MAPT | |
| SCHEMBL5264598 | 0.84 | MAPT (0.47) | PDE10APOLBLMNAALDH1A1MAPT | |
| SCHEMBL5264594 | 0.84 | MAPT (0.47) | PDE10APOLBLMNAALDH1A1MAPT | |
| SCHEMBL7814152 | 0.81 | MEN1 (0.48) | PDE10APOLBLMNAALDH1A1MAPT | |
| SCHEMBL15709862 | 0.80 | LMNA (0.61) | PDE10APOLBLMNAALDH1A1MAPT | |
| SCHEMBL3769047 | 0.80 | PDE10A (0.51) | PDE10APOLBLMNAALDH1A1MAPT | |
| SCHEMBL31213729 | 0.79 | ALDH1A1 (0.53) | PDE10APOLBLMNAALDH1A1MAPT | |
| SCHEMBL5787352 | 0.78 | MAPT (0.52) | LMNAALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL30132805 | 0.78 | MAPT (0.52) | LMNAALDH1A1MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |