Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811217 | 0.90 | PPARG (0.48) | ALDH1A1KMT2ATSHRPOLBKDM4E | |
| SCHEMBL7804727 | 0.84 | PPARG (0.53) | ALDH1A1KMT2APOLBMEN1PPARG | |
| SCHEMBL7804408 | 0.81 | PPARA (0.53) | ALDH1A1KMT2APOLBMEN1PPARG | |
| SCHEMBL7811809 | 0.80 | NAMPT (0.57) | ALDH1A1POLBKDM4EPPARGPPARA | |
| SCHEMBL7811694 | 0.80 | PPARG (0.52) | ALDH1A1PPARGPPARASMN1; SMN2 | |
| SCHEMBL7810105 | 0.79 | L3MBTL1 (0.68) | ALDH1A1PPARGPPARALMNASMN1; SMN2 | |
| SCHEMBL7811461 | 0.79 | NAMPT (0.52) | ALDH1A1POLBPPARGPPARAMAPT | |
| SCHEMBL7813924 | 0.79 | PPARA (0.51) | KMT2APOLBMEN1PPARGPPARA | |
| SCHEMBL7817567 | 0.79 | PPARA (0.64) | ALDH1A1KMT2AMEN1PPARGPPARA | |
| SCHEMBL7813581 | 0.79 | PPARA (0.51) | ALDH1A1KMT2APOLBMEN1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |