Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7813758 | 0.90 | L3MBTL1 (0.66) | L3MBTL1PPARGPPARAKCNA5ALDH1A1 | |
| SCHEMBL7804727 | 0.84 | PPARG (0.53) | L3MBTL1PPARGPPARAALDH1A1SMN1; SMN2 | |
| SCHEMBL7811694 | 0.82 | PPARG (0.52) | L3MBTL1PPARGPPARAALDH1A1HTT | |
| SCHEMBL7804408 | 0.81 | PPARA (0.53) | L3MBTL1PPARGPPARAALDH1A1PKM | |
| SCHEMBL9011204 | 0.80 | PPARA (0.48) | L3MBTL1PPARGPPARAALDH1A1SMN1; SMN2 | |
| SCHEMBL7811809 | 0.80 | NAMPT (0.57) | PPARGPPARAALDH1A1GAAHTT | |
| SCHEMBL7814247 | 0.79 | ALDH1A1 (0.53) | PPARGPPARAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7809900 | 0.79 | PPARA (0.49) | PPARGPPARA | |
| SCHEMBL7813924 | 0.79 | PPARA (0.51) | PPARGPPARA | |
| SCHEMBL7811461 | 0.79 | NAMPT (0.52) | PPARGPPARAALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |