SCHEMBL548547

SCHEMBL548547

NNC(=O)CC(=S)N(NC(=O)c1ccccc1O)C(=O)c1ccccc1O

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA1 P00915 6/20 0.47
CA9 Q16790 6/20 0.47
KDM4E B2RXH2 3/20 0.41
GAA P10253 2/20 0.41
MPO P05164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HIF1A Q16665 1/20 0.41
L1CAM P32004 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
TSHR P16473 1/20 0.39
LMNA P02545 2/20 0.39
TP53 P04637 2/20 0.39
HTT P42858 2/20 0.39
HPGD P15428 1/20 0.39
HSD17B10 Q99714 1/20 0.39
NPC1 O15118 1/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9014827 0.83 CA1 (0.42) CA1CA9KDM4EGAAMPO
SCHEMBL11689088 0.83 GAA (0.41) CA1CA9KDM4EGAAMPO
SCHEMBL1133172 0.82 CA1 (0.43) CA1CA9KDM4EGAAMPO
SCHEMBL9067407 0.82 CA1 (0.50) CA1CA9KDM4EGAAMPO
SCHEMBL11328037 0.81 KDM4E (0.47) CA1CA9KDM4EGAAMPO
SCHEMBL6436974 0.81 KDM4E (0.39) CA1CA9KDM4EGAAMPO
SCHEMBL28261515 0.80 NAAA (0.39) CA1CA9KDM4EGAAMPO
SCHEMBL11321424 0.80 NAAA (0.39) CA1CA9KDM4EGAAMPO
SCHEMBL29966079 0.79 KDM4E (0.45) CA1CA9KDM4EGAAMPO
SCHEMBL78143 0.79 KDM4E (0.45) CA1CA9KDM4EGAAMPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 394 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0108714-A1 Dibenzodioxaphosphepine and dioxaphosphocine processing stabilizers CIBA-GEIGY AG (CH) 1984-05-16 EP claimed
US-11859084-B2 Flame-retardant and color-stable polyamide molding compounds CLARIANT INTERNATIONAL LTD (CH) 2024-01-02 US disclosed
EP-3697835-B1 FLAME-RETARDANT AND COLOR-STABLE POLYAMIDE MOLDING COMPOUNDS CLARIANT INT LTD (CH) 2021-12-08 EP disclosed
US-11053375-B2 Anticorrosive flame retardant formulations for thermoplastic polymers CLARIANT PLASTICS & COATINGS LTD (CH) 2021-07-06 US disclosed
US-20200277491-A1 FLAME-RETARDANT AND COLOR-STABLE POLYAMIDE MOLDING COMPOUNDS CLARIANT PLASTICS & COATINGS LTD (CH) 2020-09-03 US disclosed
EP-3697835-A1 FLAME-RETARDANT AND COLOR-STABLE POLYAMIDE MOLDING COMPOUNDS Clariant Plastics & Coatings Ltd (CH) 2020-08-26 EP disclosed
US-20190153197-A1 Flame Retardant-Stabilizer Combination For Thermoplastic Polymers CLARIANT INTERNATIONAL LTD (CH) 2019-05-23 US disclosed
WO-2019076688-A1 FLAME-RETARDANT AND COLOR-STABLE POLYAMIDE MOLDING COMPOUNDS CLARIANT PLASTICS & COATINGS LTD (CH) 2019-04-25 WO disclosed
US-20180171112-A1 ANTICORROSIVE FLAME RETARDANT FORMULATIONS FOR THERMOPLASTIC POLYMERS CLARIANT PLASTICS & COATINGS LTD (CH) 2018-06-21 US disclosed
EP-3313920-A1 ANTICORROSIVE FLAME RETARDANT FORMULATIONS FOR THERMOPLASTIC POLYMERS Clariant Plastic & Coatings Ltd (CH) 2018-05-02 EP disclosed
US-4187212-A Stabilization systems from triarylphosphites and phenols CIBA-GEIGY CORPORATION (US) 1980-02-05 US disclosed
US-4182704-A STABILIZERS CIBA-GEIGY CORPORATION (US) 1980-01-08 US disclosed
US-4180497-A STABILIZERS FOR ORGANIC POLYMERS AGAINST THERMAL, OXIDATIVE AND UV LIGHT DEGRADATION CIBA-GEIGY CORPORATION (US) 1979-12-25 US disclosed
US-4180498-A STABILIZERS OF POLYMERS AGAINST THERMAL, OXIDATIVE, AND ULTRAVIOLET LIGHT DEGRADATION CIBA-GEIGY CORPORATION (US) 1979-12-25 US disclosed
EP-0004026-A1 Hydrolytically stable ortho-alkylated phenyl phosphonites and stabilized compositions CIBA-GEIGY AG (CH) 1979-09-19 EP disclosed
US-4143028-A Alkylated 1,1'-biphenyl-2,2'-diyl phosphonites and stabilized compositions CIBA-GEIGY CORPORATION (US) 1979-03-06 US disclosed
US-4134879-A AGING RESISTANCE, COLORFASTNESS CIBA-GEIGY CORPORATION (US) 1979-01-16 US disclosed
US-4094855-A Hindered phenyl phosphites CIBA-GEIGY CORPORATION (US) 1978-06-13 US disclosed
US-4069196-A Piperidyl esters of higher di-tri-, and polybasic aliphatic carboxylic acids as stabilizers for polymeric materials CIBA-GEIGY CORPORATION (US) 1978-01-17 US disclosed
US-4013619-A STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1977-03-22 US disclosed