SCHEMBL7814523

SCHEMBL7814523

Cc1ccc2cccc(OCc3c(Cl)ccc(S(=O)(=O)N4CCC[C@H]4C(=O)N4CCN(C=NN)CC4)c3Cl)c2n1

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RORC P51449 13/20 0.60
BDKRB2 P30411 7/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7959557 0.99 RORC (0.60) RORCBDKRB2
SCHEMBL7810998 0.92 RORC (0.58) RORCBDKRB2
SCHEMBL7805387 0.92 RORC (0.57) RORCBDKRB2
Hydrochloric Acid SCHEMBL7959615 0.91 RORC (0.57) RORCBDKRB2
SCHEMBL7812555 0.90 RORC (0.67) RORCBDKRB2
SCHEMBL7814526 0.89 BDKRB2 (0.68) RORCBDKRB2
SCHEMBL7814521 0.89 BDKRB2 (0.68) RORCBDKRB2
SCHEMBL7814484 0.89 RORC (0.63) RORCBDKRB2
Hydrochloric Acid SCHEMBL7959552 0.89 BDKRB2 (0.67) RORCBDKRB2
Hydrochloric Acid SCHEMBL7959551 0.89 BDKRB2 (0.67) RORCBDKRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0874841-B1 1-BENZENESULFONYL PYRROLIDINE DERIVATIVES AS BRADYKININ RECEPTOR ANTAGONISTS FOURNIER IND & SANTE (FR) 2001-10-04 EP disclosed