SCHEMBL7814548

SCHEMBL7814548

[CH2]CC(=O)OC(C)(C)C(=O)OC

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.40
TSHR P16473 3/20 0.33
HSD17B10 Q99714 1/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
TP53 P04637 1/20 0.31
RAB9A P51151 1/20 0.31
TET2 Q6N021 1/20 0.30
LMNA P02545 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
CA12 O43570 1/20 0.30
CA2 P00918 1/20 0.30
CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4675922 0.80 DGAT1 (0.41) DGAT1TSHRHSD17B10MGAMGAA
SCHEMBL7817817 0.79 LMNA (0.36) TSHRLMNAKMT2ASMN1; SMN2
SCHEMBL26292497 0.78 DGAT1 (0.40) DGAT1TSHRHSD17B10MGAMGAA
SCHEMBL7815186 0.77 PPARA (0.33) TSHRTET2KMT2A
SCHEMBL24160913 0.77 ALDH1A1 (0.44) DGAT1TSHRLMNACA12CA2
SCHEMBL4677117 0.77 DGAT1 (0.46) DGAT1TP53RAB9ALMNAKMT2A
SCHEMBL26296844 0.75 DGAT1 (0.38) DGAT1TSHRKMT2A
SCHEMBL7817361 0.75 TSHR (0.39) TSHRSMN1; SMN2
SCHEMBL7817788 0.75
SCHEMBL297179 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1112268-A1 CONDENSED HETEROCYCLIC COMPOUNDS AND HERBICIDES CONTAINING THEM SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2001-07-04 EP disclosed
WO-2000021936-A1 URACIL HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-04-20 WO disclosed
WO-2000015633-A1 CONDENSED HETEROCYLIC COMPOUNDS AND HERBICIDES CONTAINING THEM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-03-23 WO disclosed