Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7813709 | 0.67 | CRHR1 (0.38) | CRHR1 | |
| SCHEMBL16998390 | 0.60 | CRHR1 (0.47) | CRHR1 | |
| SCHEMBL27985528 | 0.60 | CRHR1 (0.42) | CRHR1 | |
| SCHEMBL7034371 | 0.60 | — | — | |
| SCHEMBL17612778 | 0.59 | HSD11B1 (0.43) | CRHR1 | |
| SCHEMBL7035426 | 0.59 | — | — | |
| SCHEMBL8148384 | 0.57 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL7583757 | 0.56 | HSD11B1 (0.50) | CRHR1 | |
| SCHEMBL13677229 | 0.55 | CNR2 (0.54) | — | |
| SCHEMBL12871641 | 0.55 | CRHR1 (0.53) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091941-A1 | NOVEL BENZIMIDAZOLES AS CORTICOTROPIN RELEASE FACTOR ANTAGONISTS | Du Pont Pharmaceuticals Company (US) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001675-A1 | NOVEL BENZIMIDAZOLES AS CORTICOTROPIN RELEASE FACTOR ANTAGONISTS | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-01-13 | — | — | WO | disclosed |