Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.44 |
| ▸ | CRHR1 | P34998 | 4/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25294617 | 0.81 | CYP3A4 (0.52) | HSP90AA1HSP90AB1KMT2AMEN1ALDH1A1 | |
| SCHEMBL30522557 | 0.81 | CYP3A4 (0.52) | HSP90AA1HSP90AB1KMT2AMEN1ALDH1A1 | |
| SCHEMBL17612778 | 0.74 | HSD11B1 (0.43) | HSD11B1HSP90AA1HSP90AB1CRHR1AHR | |
| SCHEMBL4452962 | 0.74 | AHR (0.56) | HSD11B1HSP90AA1HSP90AB1AHRALDH1A1 | |
| SCHEMBL14206717 | 0.71 | CNR1 (0.44) | KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL29624840 | 0.71 | AHR (0.64) | HSD11B1HSP90AA1HSP90AB1CRHR1AHR | |
| SCHEMBL464507 | 0.71 | AHR (0.64) | HSD11B1HSP90AA1HSP90AB1CRHR1AHR | |
| SCHEMBL4445166 | 0.70 | AHR (0.58) | HSD11B1HSP90AA1HSP90AB1AHRALDH1A1 | |
| SCHEMBL7578666 | 0.69 | HSD11B1 (0.50) | HSD11B1HSP90AA1HSP90AB1CRHR1KMT2A | |
| SCHEMBL2963945 | 0.69 | TSHR (0.44) | HSD11B1HSP90AA1HSP90AB1CRHR1AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773248-B1 | Polymers with heterocyclic side groups | MISSISSIPPI POLYMER TECHNOLOGI (US) | 2002-10-02 | — | — | EP | disclosed |
| US-5668245-A | PHENYLENE POLYMERS WITH HETEROCYCLIC SIDE GROUPS | MAXDEM INCORPORATED (US) | 1997-09-16 | — | — | US | disclosed |
| EP-0773248-A1 | Polymers with heterocyclic side groups | MAXDEM INCORPORATED (US) | 1997-05-14 | — | — | EP | disclosed |