Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 16/20 | 0.58 |
| ▸ | BDKRB2 | P30411 | 4/20 | 0.53 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8187943 | 0.99 | RORC (0.58) | RORCBDKRB2BDKRB1 | |
| SCHEMBL7814639 | 0.88 | BDKRB2 (0.63) | RORCBDKRB2BDKRB1 | |
| SCHEMBL7815487 | 0.88 | RORC (0.59) | RORCBDKRB2BDKRB1 | |
| Hydrochloric Acid SCHEMBL8187935 | 0.87 | BDKRB2 (0.63) | RORCBDKRB2BDKRB1 | |
| SCHEMBL7812505 | 0.87 | RORC (0.60) | RORCBDKRB2BDKRB1 | |
| SCHEMBL7812751 | 0.87 | RORC (0.60) | RORCBDKRB2BDKRB1 | |
| Hydrochloric Acid SCHEMBL8188635 | 0.87 | RORC (0.59) | RORCBDKRB2BDKRB1 | |
| SCHEMBL7814638 | 0.86 | RORC (0.58) | RORCBDKRB2BDKRB1 | |
| SCHEMBL6952228 | 0.84 | BDKRB2 (0.69) | RORCBDKRB2BDKRB1 | |
| SCHEMBL7818479 | 0.84 | RORC (0.54) | RORCBDKRB2BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925295-B1 | N-BENZENESULPHONYL-L-PROLINE DERIVATIVES AS B2 RECEPTOR ANTAGONISTS OF THE BRADYKININ | FOURNIER IND & SANTE (FR) | 2001-10-04 | — | — | EP | disclosed |
| EP-0925295-A1 | N-BENZENESULPHONYL-L-PROLINE DERIVATIVES AS BRADYKININ B2 AGONISTS | FOURNIER INDUSTRIE ET SANTE (FR) | 1999-06-30 | — | — | EP | disclosed |
| WO-1998003503-A1 | N-BENZENESULPHONYL-L-PROLINE DERIVATIVES AS BRADYKININ B2 AGONISTS | FOURNIER INDUSTRIE ET SANTE (FR) | 1998-01-29 | — | — | WO | disclosed |