Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 14/20 | 0.59 |
| ▸ | BDKRB2 | P30411 | 5/20 | 0.57 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7814639 | 0.94 | BDKRB2 (0.63) | RORCBDKRB2BDKRB1TP53POLB | |
| Hydrochloric Acid SCHEMBL8187935 | 0.93 | BDKRB2 (0.63) | RORCBDKRB2BDKRB1TP53POLB | |
| SCHEMBL7814638 | 0.90 | RORC (0.58) | RORCBDKRB2BDKRB1TP53POLB | |
| SCHEMBL7814645 | 0.88 | RORC (0.58) | RORCBDKRB2BDKRB1 | |
| SCHEMBL7812751 | 0.88 | RORC (0.60) | RORCBDKRB2BDKRB1 | |
| Hydrochloric Acid SCHEMBL8187943 | 0.87 | RORC (0.58) | RORCBDKRB2BDKRB1 | |
| SCHEMBL7814943 | 0.87 | BDKRB2 (0.62) | RORCBDKRB2BDKRB1 | |
| SCHEMBL7815597 | 0.84 | RORC (0.65) | RORCBDKRB2BDKRB1 | |
| SCHEMBL7805147 | 0.84 | BDKRB2 (0.64) | RORCBDKRB2BDKRB1 | |
| SCHEMBL7951571 | 0.83 | RORC (0.64) | RORCBDKRB2BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925295-B1 | N-BENZENESULPHONYL-L-PROLINE DERIVATIVES AS B2 RECEPTOR ANTAGONISTS OF THE BRADYKININ | FOURNIER IND & SANTE (FR) | 2001-10-04 | — | — | EP | disclosed |
| US-6071917-A | ANALGESICS; ANTIINFLAMMATORY AGENTS; ESPECIALLY FOR THE TREATMENT OF ASTHMA, CEREBRAL TRAUMATIC SHOCK AND ALLERGIC RHINITIS; COMPETITIVE BINDING AT RECEPTORS | FOURNIER INDUSTRIE ET SANTE (FR) | 2000-06-06 | — | — | US | disclosed |