Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3049870 | 0.89 | KMT2A (0.49) | MAPTKDM4EKMT2AMEN1RCE1 | |
| SCHEMBL3059360 | 0.85 | KDM4E (0.64) | MAPTKDM4EKMT2AMEN1RCE1 | |
| SCHEMBL2996737 | 0.83 | MAPT (0.70) | MAPTKDM4EKMT2AMEN1NPSR1 | |
| SCHEMBL2995982 | 0.82 | NR3C2 (0.60) | MAPTKDM4EKMT2AMEN1RCE1 | |
| SCHEMBL9401663 | 0.81 | KDM4E (0.58) | MAPTKDM4EKMT2AMEN1RCE1 | |
| SCHEMBL3016302 | 0.79 | ALDH1A1 (0.62) | MAPTKDM4EKMT2AMEN1NPSR1 | |
| SCHEMBL11829270 | 0.79 | CYP2C9 (0.67) | MAPTKDM4EKMT2AMEN1RCE1 | |
| SCHEMBL202183 | 0.77 | CACNA1C (0.73) | MAPTKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL29358809 | 0.77 | CACNA1C (0.73) | MAPTKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL20954359 | 0.76 | FFAR3 (0.47) | MAPTKMT2AMEN1NR3C2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109070-A2 | 1,4-Dihydropyridine charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY (US) | 2001-06-20 | — | — | EP | disclosed |