Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | CACNA1F | O60840 | 4/20 | 0.58 |
| ▸ | CACNA1D | Q01668 | 4/20 | 0.58 |
| ▸ | CACNA1S | Q13698 | 4/20 | 0.58 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.58 |
| ▸ | SCN1A | P35498 | 3/20 | 0.58 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.58 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3059360 | 0.95 | KDM4E (0.64) | KDM4EHSD17B10KMT2ACYP2C9ADORA3 | |
| SCHEMBL3049870 | 0.91 | KMT2A (0.49) | KDM4EHSD17B10KMT2ACYP2C9ADORA3 | |
| SCHEMBL11829270 | 0.88 | CYP2C9 (0.67) | KDM4EHSD17B10KMT2ACYP2C9ADORA3 | |
| SCHEMBL11004464 | 0.82 | CYP1A2 (0.68) | KDM4EHSD17B10KMT2ACYP2C9ADORA3 | |
| SCHEMBL11004457 | 0.82 | CYP1A2 (0.68) | KDM4EHSD17B10KMT2ACYP2C9ADORA3 | |
| SCHEMBL3034993 | 0.82 | ADORA3 (0.57) | KDM4EHSD17B10KMT2ACYP2C9ADORA3 | |
| SCHEMBL3026759 | 0.82 | KDM4E (0.62) | KDM4EHSD17B10KMT2ACYP2C9ADORA3 | |
| SCHEMBL2996737 | 0.82 | MAPT (0.70) | KDM4EHSD17B10KMT2ACYP2C9ADORA3 | |
| SCHEMBL7414856 | 0.82 | NR1I2 (0.67) | KDM4EHSD17B10KMT2ACYP2C9ADORA3 | |
| SCHEMBL9830577 | 0.81 | CACNA1B (0.63) | KMT2AADORA3CACNA1CCACNA1BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286869-A | Vasodilators and anticoagulants | FUJIREBIO KABUSHIKI KAISHA (JP) | 1994-02-15 | — | — | US | disclosed |
| EP-0403957-A2 | Optical active 1,4-dihydropyridine derivates | FUJIREBIO INC. (JP) | 1990-12-27 | — | — | EP | disclosed |
| US-4532248-A | Administering 1,4-dihydropyridine derivative exhibiting positive inotropic activity | BAYER AKTIENGESELLSCHAFT (DE) | 1985-07-30 | — | — | US | disclosed |