Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 9/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7802439 | 0.92 | ALOX5 (0.85) | ALOX5LMNAL3MBTL1OPRD1OPRK1 | |
| SCHEMBL7808961 | 0.89 | ALOX5 (0.80) | ALOX5OPRD1OPRK1OPRM1 | |
| SCHEMBL332442 | 0.84 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL29405839 | 0.84 | ALOX5 (1.00) | ALOX5 | |
| Hydrochloric Acid SCHEMBL8173877 | 0.84 | ALOX5 (0.98) | ALOX5 | |
| SCHEMBL7809017 | 0.83 | ALOX5 (1.00) | ALOX5LMNAOPRD1OPRK1OPRM1 | |
| SCHEMBL6573790 | 0.81 | ALOX5 (0.93) | ALOX5 | |
| SCHEMBL14678487 | 0.79 | ALOX5 (0.79) | ALOX5 | |
| SCHEMBL332479 | 0.78 | ALOX5 (0.65) | ALOX5LMNA | |
| SCHEMBL7656075 | 0.78 | ALOX5 (0.69) | ALOX5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787127-B1 | 5-LIPOXYGENASE INHIBITORS | PFIZER (US) | 2001-01-03 | — | — | EP | disclosed |
| US-6063928-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, CARDIOTONIC AGENTS | PFIZER INC (US) | 2000-05-16 | — | — | US | disclosed |