Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 20/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 16/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 16/20 | 0.50 |
| ▸ | GABRP | O00591 | 13/20 | 0.50 |
| ▸ | GABRD | O14764 | 13/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 13/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 13/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 13/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 13/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 13/20 | 0.50 |
| ▸ | GABRA4 | P48169 | 13/20 | 0.50 |
| ▸ | GABRE | P78334 | 13/20 | 0.50 |
| ▸ | GABRA6 | Q16445 | 13/20 | 0.50 |
| ▸ | GABRG1 | Q8N1C3 | 13/20 | 0.50 |
| ▸ | GABRG3 | Q99928 | 13/20 | 0.50 |
| ▸ | GABRQ | Q9UN88 | 13/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7812962 | 0.87 | GABRA2 (0.60) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9780269 | 0.84 | GABRB3 (0.53) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7811860 | 0.81 | GABRB3 (0.50) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7811859 | 0.81 | GABRB3 (0.50) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7811856 | 0.79 | GABRP (0.57) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7811853 | 0.79 | GABRP (0.57) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7811854 | 0.79 | GABRP (0.57) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7805643 | 0.79 | GABRB3 (0.51) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7022491 | 0.78 | GABRB3 (0.55) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL2835177 | 0.78 | GABRB3 (0.50) | GABRB3GABRA2GABRB2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871617-B1 | PARASITICIDAL COMPOUNDS | PFIZER (US) | 2001-11-14 | — | — | EP | disclosed |
| US-6255333-B1 | HUMANS OR ANIMALS | PFIZER INC. | 2001-07-03 | — | — | US | disclosed |
| EP-0871617-A1 | PARASITICIDAL COMPOUNDS | PFIZER INC. (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997007102-A1 | PARASITICIDAL COMPOUNDS | PFIZER INC (US) | 1997-02-27 | — | — | WO | disclosed |