Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMPD2 | O60906 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10786707 | 1.00 | ALDH1A1 (0.40) | ALDH1A1LMNATP53SMN1; SMN2NPSR1 | |
| SCHEMBL28187208 | 0.87 | ALDH1A1 (0.41) | ALDH1A1LMNATP53SMN1; SMN2NPSR1 | |
| SCHEMBL31016233 | 0.84 | KMT2A (0.50) | SMN1; SMN2NPSR1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL12466932 | 0.80 | LMNA (0.37) | ALDH1A1LMNATP53SMN1; SMN2NPSR1 | |
| SCHEMBL10784586 | 0.80 | NPSR1 (0.41) | ALDH1A1LMNATP53SMN1; SMN2NPSR1 | |
| SCHEMBL6743611 | 0.80 | ALDH1A1 (0.38) | ALDH1A1LMNATP53SMN1; SMN2NPSR1 | |
| SCHEMBL149788 | 0.79 | ALDH1A1 (0.40) | ALDH1A1LMNATP53SMN1; SMN2NPSR1 | |
| SCHEMBL6743610 | 0.78 | KMT2A (0.37) | ALDH1A1LMNATP53SMN1; SMN2NPSR1 | |
| SCHEMBL10645063 | 0.78 | GABRA1 (0.37) | ALDH1A1TP53TSHRSMPD2PGR | |
| SCHEMBL23213653 | 0.77 | GRN (0.36) | ALDH1A1SMN1; SMN2TSHRHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0164389-B1 | PREPARATION OF PHENYL ALANINES BY HYDROGENATION OF PHENYL SERINES | ALKALOIDA VEGYéSZETI GYáR (HU) | 1987-04-01 | — | — | EP | claimed |
| EP-0164389-A1 | PREPARATION OF PHENYL ALANINES BY HYDROGENATION OF PHENYL SERINES. | ALKALOIDA VEGYESZETI GYAR (HU) | 1985-12-18 | — | — | EP | claimed |
| WO-1985002609-A1 | PREPARATION OF PHENYL ALANINES BY HYDROGENATION OF PHENYL SERINES | ALKALOIDA VEGYÉSZETI GYÁR (HU) | 1985-06-20 | — | — | WO | claimed |
| EP-0673936-B1 | Antithrombotic agents | LILLY CO ELI (US) | 2001-02-07 | — | — | EP | disclosed |
| EP-0670310-B1 | Bisulfite adducts of arginine aldehydes useful as thrombin inhibitors and as anticoagulants | LILLY CO ELI (US) | 1998-09-02 | — | — | EP | disclosed |
| EP-0673936-A1 | Antithrombotic agents | ELI LILLY AND COMPANY (US) | 1995-09-27 | — | — | EP | disclosed |
| EP-0670310-A1 | Bisulfite adducts of arginine aldehydes useful as thrombin inhibitors and as anticoagulants | ELI LILLY AND COMPANY (US) | 1995-09-06 | — | — | EP | disclosed |