Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | NSD2 | O96028 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.48 |
| ▸ | MAOA | P21397 | 3/20 | 0.48 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.48 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.48 |
| ▸ | CSNK1G1 | Q9HCP0 | 2/20 | 0.48 |
| ▸ | FGR | P09769 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.48 |
| ▸ | PTPRC | P08575 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29563346 | 0.82 | RAB9A (0.68) | NPC1RAB9APOLBALDH1A1NSD2 | |
| SCHEMBL1510327 | 0.82 | RAB9A (0.68) | NPC1RAB9APOLBALDH1A1NSD2 | |
| SCHEMBL28227189 | 0.82 | CDC25B (0.65) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL27587283 | 0.79 | CDC25B (0.61) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL16745451 | 0.75 | RAB9A (0.60) | NPC1RAB9APOLBALDH1A1NSD2 | |
| Anthraquinone SCHEMBL10771377 | 0.73 | MEN1 (0.92) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL14660371 | 0.71 | ALDH1A1 (1.00) | NPC1RAB9APOLBALDH1A1NSD2 | |
| SCHEMBL14662957 | 0.71 | NPC1 (0.56) | NPC1RAB9APOLBALDH1A1NSD2 | |
| SCHEMBL21141273 | 0.71 | CDC25B (0.56) | NPC1RAB9APOLBALDH1A1MAPT | |
| SCHEMBL21141483 | 0.71 | IDO1 (0.68) | NPC1RAB9APOLBALDH1A1NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61251675-A | — | — | None | — | — | JP | disclosed |
| CN-1440966-A | Naphthaquinone thiazole as organic as third-order non-linear optical material and its chemical synthesis process | UNIV ZHEJIANG POLYTECHNIC (CN) | 2003-09-10 | — | — | CN | disclosed |
| EP-0876356-B1 | USE OF TRICYCLIC 1,4-DIHYDRO-1,4-DIOXO-1H-NAPHTHALENE DERIVATIVES, RESULTING NOVEL COMPOUNDS AND THERAPEUTICAL USE THEREOF | INNOTHERA SA LAB (FR) | 2001-10-31 | — | — | EP | disclosed |
| US-6262095-B1 | TREATMENT OF ILLNESS ASSOCIATED WITH AN ALTERATION IN VENOUS FUNCTION AND/OR INFLAMMATORY EDEMA | LABORATOIRE INNOTHERA (FR) | 2001-07-17 | — | — | US | disclosed |
| WO-1998037076-A1 | METHOD FOR INDUSTRIAL PRODUCTION OF NAPHTO-[2,3-D]-THIAZOLE COMPOUNDS | INNOKEM, S.A.R.L. (FR) | 1998-08-27 | — | — | WO | disclosed |
| JP-S61251675-A | PRODUCTION OF NAPHTHO(2.3-D)THIAZOLE-4,9-DIONE COMPOUND | KAWASAKI KASEI CHEM LTD | 1986-11-08 | — | — | JP | disclosed |