Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 9/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 6/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7807339 | 0.94 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| Trifluoroacetic Acid SCHEMBL7818314 | 0.86 | CAMK2D (0.48) | MAPTALDH1A1KDM4EGAAHPGD | |
| Trifluoroacetic Acid SCHEMBL7806936 | 0.79 | CFTR (0.49) | ALDH1A1USP2CYP1A2CASP1CASP7 | |
| Trifluoroacetic Acid SCHEMBL8368538 | 0.79 | CFTR (0.42) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| Trifluoroacetic Acid SCHEMBL8516337 | 0.79 | LMNA (0.47) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| Trifluoroacetic Acid SCHEMBL8362203 | 0.78 | CFTR (0.41) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| Acetic Acid SCHEMBL7815108 | 0.78 | CAMK2D (0.51) | MAPTALDH1A1KDM4EGAAHPGD | |
| Trifluoroacetic Acid SCHEMBL8366714 | 0.78 | LMNA (0.43) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| Trifluoroacetic Acid SCHEMBL7815291 | 0.77 | CAMK2D (0.46) | MAPTALDH1A1USP2CYP1A2CASP1 | |
| Trifluoroacetic Acid SCHEMBL8367897 | 0.77 | CFTR (0.40) | PDE4APDE4BPDE4CPDE4DPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010025043-A1 | New pharmaceutical active compounds | ASTRA AKTIEBOLAG, A SWEDEN CORPORATION | 2001-09-27 | — | — | US | disclosed |
| US-6271231-B1 | Pharmaceutically active compounds | ASTRA AKTIEBOLAG (SE) | 2001-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010025043-A1 | New pharmaceutical active compounds | CSNK1A1, CSNK1G1, CSNK2A1 | PDE4A 228/4885PDE4B 342/4885PDE4C 247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.