Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
| ▸ | MASP2 | O00187 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6988652 | 0.78 | ADAM17 (0.32) | ADAM17 | |
| SCHEMBL6982108 | 0.77 | ADAM17 (0.33) | ADAM17CTSC | |
| SCHEMBL6985159 | 0.77 | ADAM17 (0.33) | ADAM17CTSC | |
| Hydrochloric Acid SCHEMBL6984767 | 0.74 | ADAM17 (0.30) | ADAM17CTSC | |
| Hydrochloric Acid SCHEMBL6984245 | 0.74 | ADAM17 (0.30) | ADAM17CTSC | |
| Hydrochloric Acid SCHEMBL6982151 | 0.74 | CTSC (0.35) | ADAM17CTSCMASP2HTR2A | |
| SCHEMBL6941953 | 0.73 | ADAM17 (0.39) | ADAM17CTSCMASP2HTR2A | |
| SCHEMBL6986382 | 0.72 | TGFBR1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL6982639 | 0.72 | CTSC (0.36) | ADAM17CTSCMASP2HTR2A | |
| SCHEMBL6983057 | 0.71 | ADAM17 (0.33) | ADAM17CTSCMASP2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089964-A1 | HYDRAZINE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2001-04-11 | — | — | EP | disclosed |
| WO-2000000465-A1 | HYDRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-01-06 | — | — | WO | disclosed |